The 49d9fcbd-d767eea6 identifies the lun which exited from the APD state. Identify which datastore (lun) that is and verify that all your hosts in the cluster see it.
Also not sure if you screen capture is complete, I see LUNS 0,1,2,4 and 7 active paths in that screen capture. So if there are no more active paths to be seen by scrolling down, something is not adding up there. Should you have a lun 3?